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FANCL
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Summary
General Info
Body Atlas
Most Correlated Tissues
Granulocyte-macrophage progenitor cell of bone marrow
Pituitary gland
Hematopoietic stem cell of bone marrow
Substantia nigra pars compacta
Midbrain
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Disease Atlas
Most Correlated Diseases
Gonadal dysgenesis
Platelet count below reference range
Platelet disorder
Anemia
Blood coagulation disorder
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Pharmaco Atlas
Most Correlated Compounds
dimethyl phthalate
Harmine
calycanthine
4-phenylbutyric acid
Digitoxigenin
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Knockdown Atlas
Most Correlated Gene Perturbations
MIR365A
DEAF1
EIF3A
TLR4
C13orf42
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
An acquired BMF with FANCL gene heterozygous mutation: Case report.
FANCL gene mutations in premature ovarian insufficiency.
FANCL supports Parkin-mediated mitophagy in a ubiquitin ligase-independent manner.
Characterization of FANCL variants observed in patient cancer cells.
A founder variant in the South Asian population leads to a high prevalence of FANCL Fanconi anemia c…
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Clinical Trials
Most Relevant Clinical Trials
Study of Olaparib in Metastatic Renal Cell Carcinoma Patients With DNA Repair Gene Mutations
Niraparib Before Surgery in Treating Patients With High Risk Localized Prostate Cancer and DNA Damag…
Niraparib as First Line Therapy With Metastatic Homologous Repair-deficient Pancreatic Cancer
Men at High Genetic Risk for Prostate Cancer
Talazoparib in Advanced Breast Cancer Patients With Homologous Recombinant Deficiency
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