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QuickView for Fluvastatin (compound)


Genetic Markers

Most Correlated Genes

  1. HMGCR
  2. NFE2
  3. FBXW5
  4. TUBA1A
  5. TUSC3
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. organic cyclic compound binding
  3. heterocyclic compound binding
  4. organic cyclic compound metabolic process
  5. heterocycle metabolic process
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Curated Studies

Most Correlated Studies

  1. Breast cancer MCF7 and MDA-MB-231 cells treated with fluvastatin
  2. Breast adenocarcinoma MDA-MB-231 cells treated with zoledronate or fluvastatin
  3. Drug target sets for approved compounds
  4. Broad Connectivity Map (CMAP 2.0) compound database
  5. Livers of rat exposed to variety of hepatotoxic compounds
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Literature

Most Relevant Literature

  1. Fluvastatin Induces Apoptosis in Primary and Transformed Mast Cells.
  2. Optimized Conjugation of Fluvastatin to HIV-1 TAT Displays Enhanced Pro-Apoptotic Activity in HepG2 …
  3. Preventive effect of fluvastatin on the development of medication-related osteonecrosis of the jaw.
  4. Fluvastatin potentiates anticancer activity of vorinostat in renal cancer cells.
  5. Plasma mevalonic acid exposure as a pharmacodynamic biomarker of fluvastatin/atorvastatin in healthy…
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Clinical Trials

Most Relevant Clinical Trials

  1. Effects of Fluvastatin on Proinflammatory and Prothrombotic Markers in Antiphospholipid Syndrome Pat…
  2. Drug-Drug Interaction Between Rifampin and Fluvastatin
  3. Fluvastatin AmelIorates aTHerosclerosis Study
  4. Fluvastatin Versus Hepatitis C Virus
  5. Effect of Fluvastatin on Brown Fat Activity
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