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GCH1
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General Info
Body Atlas
Most Correlated Tissues
T Lymphocyte (regulatory) of peripheral blood
Monocyte of peripheral blood
Myeloid cells of peripheral blood
Macrophage of peripheral blood
Liver
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Disease Atlas
Most Correlated Diseases
Hyperphenylalaninemia
Classical phenylketonuria
Alpha-1-antitrypsin deficiency
Brucellosis
Disorder of digestive system
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Pharmaco Atlas
Most Correlated Compounds
Fendiline
PDGFD protein, human
Lymphotoxin-beta
Gene Products, pol
ellipticine
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Knockdown Atlas
Most Correlated Gene Perturbations
AGO1
Stat3
EZR
SOD2
NAMPT
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
Inter and intra-generational phenotypic variability in a Portuguese family with DYT-GCH1.
GCH1 mutations in hereditary spastic paraplegia.
SPY1 inhibits neuronal ferroptosis in amyotrophic lateral sclerosis by reducing lipid peroxidation t…
Oxidative Stress, GTPCH1, and Endothelial Nitric Oxide Synthase Uncoupling in Hypertension.
Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediate…
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Clinical Trials
Most Relevant Clinical Trials
Sensorimotor Integration in Monogenic Parkinson-dystonia Syndromes
Genetics and Pain Severity in Sickle Cell Disease
A Study for Assessing the Efficacy and Safety of BH4 in Radiation Enteritis
A Study for Assessing the Efficacy and Safety of Tetrahydrobiopterin in Radiation-Induced Skin Injur…
Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section
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