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GDC-0941
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General Info
Genetic Markers
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No genes found
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Pathway Enrichment
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No biogroups found
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Curated Studies
Most Correlated Studies
Comparison of gene expression alterations induced by distinct PI3K inhibitors
T-lineage acute lymphoblastic leukemia (T-ALL) xenografts treated with GDC-0941 and PD 0325901
Acute myelogenous leukemia cells expressing activated NRAS treated with RAS pathway inhibitors
Human breast cancer cell (T47D) gene expression after treatment with GDC-0941
Endogenous expression of an oncogenic PI3K mutation in MCF10A cell line
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Literature
Most Relevant Literature
GDC-0941 enhances the lysosomal compartment via TFEB and primes glioblastoma cells to lysosomal memb…
Preclinical pharmacokinetics of the novel PI3K inhibitor GDC-0941 and prediction of its pharmacokine…
PK-PD modeling of combination efficacy effect from administration of the MEK inhibitor GDC-0973 and …
The antitumor effect of GDC-0941 alone and in combination with rapamycin in breast cancer cells.
GDC-0941 sensitizes breast cancer to ABT-737 in vitro and in vivo through promoting the degradation …
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Clinical Trials
Most Relevant Clinical Trials
A Study to Determine the Relative Bioavailability of a Tablet Formulation of GDC-0941 and the Effect…
Study of GDC-0941 or GDC-0980 With Fulvestrant Versus Fulvestrant in Advanced or Metastatic Breast C…
A Study of Paclitaxel With GDC-0941 Versus Paclitaxel With Placebo in Participants With Locally Recu…
A Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0941 and…
A Study of the Safety and Pharmacology of GDC-0941 in Combination With Erlotinib in Patients With Ad…
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