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GDC0941
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Genetic Markers
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Curated Studies
Most Correlated Studies
Comparison of gene expression alterations induced by distinct PI3K inhibitors
T-lineage acute lymphoblastic leukemia (T-ALL) xenografts treated with GDC-0941 and PD 0325901
Acute myelogenous leukemia cells expressing activated NRAS treated with RAS pathway inhibitors
Endogenous expression of an oncogenic PI3K mutation in MCF10A cell line
Human breast cancer cell (T47D) gene expression after treatment with GDC-0941
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Literature
Most Relevant Literature
GDC-0941 enhances the lysosomal compartment via TFEB and primes glioblastoma cells to lysosomal memb…
Preclinical pharmacokinetics of the novel PI3K inhibitor GDC-0941 and prediction of its pharmacokine…
PK-PD modeling of combination efficacy effect from administration of the MEK inhibitor GDC-0973 and …
The antitumor effect of GDC-0941 alone and in combination with rapamycin in breast cancer cells.
GDC-0941 sensitizes breast cancer to ABT-737 in vitro and in vivo through promoting the degradation …
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Clinical Trials
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Open Label Phase I/Randomised,Double Blind Phase II Study in mCRPC of AZD5363 In Combination With DP…
Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients …
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