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(e.g. Laryngoscope, Clofibrate, rs3825942, GATA1, T cell receptor signaling pathway)
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QuickView for GRN (gene)


Body Atlas

Most Correlated Tissues

  1. Microglial cell
  2. Macrophage of peripheral blood
  3. Lung
  4. Myeloid cells of peripheral blood
  5. Placenta
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Disease Atlas

Most Correlated Diseases

  1. Bacterial infection due to Bacillus
  2. Sepsis due to coagulase negative Staphylococcus
  3. Disease due to Orthopoxvirus
  4. Severe acute respiratory syndrome
  5. Viral disease
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Pharmaco Atlas

Most Correlated Compounds

  1. Viral Vaccines
  2. Fluvirin
  3. Bismuth
  4. Epinephrine
  5. Diaminopimelic Acid
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. DST
  2. Mir10a
  3. Ahr
  4. GRN
  5. SDC4
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. The Role of Progranulin (PGRN) in the Pathogenesis of Glioblastoma Multiforme.
  2. Progranulin deficiency attenuates tubulointerstitial injury in a mouse unilateral ureteral obstructi…
  3. Male-pronuclei-specific granulin facilitates somatic cells reprogramming via mitigating excessive ce…
  4. Dendritic spine head diameter is reduced in the prefrontal cortex of progranulin haploinsufficient m…
  5. Progranulin and neuropathological features of Alzheimer's disease: longitudinal study.
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Clinical Trials

Most Relevant Clinical Trials

  1. Phase 1 Study of GRN-1201 in HLA-A*02 Subjects With Resected Melanoma
  2. A Study of PBFT02 in Patients With Frontotemporal Dementia and Progranulin Mutations (FTD-GRN)
  3. A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With G…
  4. Dose Finding Study of Nimodipine for the Treatment of Progranulin Insufficiency From GRN Gene Mutati…
  5. Phase 1/2 Clinical Trial of PR006 in Patients With Frontotemporal Dementia With Progranulin Mutation…
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