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H1047R
Summary
General Info
Curated Studies
Most Correlated Studies
Induced pluripotent stem cells with PIK3CA-H1047R heterozygous and homozygous knockin
Fibrocystic disease of breast MCF10A cells overexpressing PIK3CA-H1047R and treated with BYL719
Induced pluripotent stem cells with PIK3CA H1047R heterozygous and homozygous mutation
Mammary tumors from mice with condition ErbB3-knockout and PIK3CA[H1047R] mutant overexpression
HMECs with BEZ235 resistance, expressing a mutant PIK3CA(H1047R) transgene, and treated with BEZ235
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Literature
Most Relevant Literature
Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein.
Identification of effective natural PIK3CA H1047R inhibitors by computational study.
Sialadenoma papilliferum-like intraductal papillary tumor with unveiling BRAF V600E and PIK3CA H1047…
Single-nucleotide variant of PIK3CA H1047R gene assay by CRISPR/Cas12a combined with rolling circle …
PIK3CA hotspot mutations p. H1047R and p. H1047L sensitize breast cancer cells to thymoquinone treat…
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Clinical Trials
Most Relevant Clinical Trials
Phase 2, Endocrine Therapy + OSI-906 With or Without Erlotinib for Hormone-sensitive Metastatic Brea…
Compassionate Use of BYL 719 Alpelisib
A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors
Study to Evaluate the Safety and Efficacy of Sirolimus, in Subject With Refractory Solid Tumors
BKM120 in Cancers With PIK3CA Activating Mutations
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