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Hedgehog receptor
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Curated Studies
Most Correlated Studies
Wnt-Bmp signaling dynamics in tooth organogenesis
Human ESC (H9) differentiation in the presence of noggin, SB431542 and SHH
Zebrafish embryos exposed to hedgehog pathway inhibitors
Articular cartilage from osteoarthritis subjects treated with Hedgehog pathway (Hh) antagonist
Sonic hedgehog medulloblastoma UI226 cells sorted for CD271
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Literature
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Expression, Purification, and Structure Determination of Human PTCH1-HH-N Complexes.
A392V and R945X mutations cause orofacial clefts via impairing PTCH1 function.
Patched 1 expression in Merkel cell carcinoma.
Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes.
PTCH1 regulates anchorage-independent growth and bone invasion of non-small cell lung cancer cells.
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Clinical Trials
Most Relevant Clinical Trials
LDE225 in Treating Patients With Stage II-III Estrogen Receptor- and HER2-Negative Breast Cancer
A Randomized Phase II Study of Cisplatin and Etoposide in Combination With Either Hedgehog Inhibitor…
Study to Evaluate the Safety and Efficacy of Treatment With NLM-001 and Standard Chemotherapy Plus Z…
Itraconazole in Non Small Cell Lung Cancer
Vismodegib Combined With Atezolizumab in Platinum Resistant Ovarian, Fallopian Tube, and Primary Per…
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