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(e.g. rs2300478, GATA1, Metabolism of xenobiotics, Obesity, Breast, Personalized medicine)
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QuickView for ICOS (gene)


Body Atlas

Most Correlated Tissues

  1. T Lymphocyte (regulatory) of peripheral blood
  2. T Lymphocyte (CD4+) of peripheral blood
  3. Natural killer cell of peripheral blood
  4. T Lymphocyte (CD8+) of peripheral blood
  5. Thymus gland
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Disease Atlas

Most Correlated Diseases

  1. Common variable immunodeficiency
  2. Mental state, behavior and/or psychosocial function finding
  3. Stachybotryotoxicosis
  4. Viral infections of the central nervous system
  5. Toxic effect of mycotoxin
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Pharmaco Atlas

Most Correlated Compounds

  1. gp50 protein, Schistosoma
  2. p40 egg antigen, Schistosoma
  3. IL8 protein, human
  4. CEP 14083
  5. 6-formylindolo(3,2-b)carbazole
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. BCOR
  2. UBE3C
  3. TPI1
  4. ADAM17
  5. LEP
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. ICOS costimulation is indispensable for the differentiation of T follicular regulatory cells.
  2. ICOS-expressing Regulatory T Cells Influence the Composition of Antitumor CTL Populations.
  3. ICOS-Deficient Regulatory T Cells Can Prevent Spontaneous Autoimmunity but Are Impaired in Controlli…
  4. Icos gene disruption in non-obese diabetic mice elicits myositis associated with anti-troponin T3 au…
  5. Acazicolcept (ALPN-101), a dual ICOS/CD28 antagonist, demonstrates efficacy in systemic sclerosis pr…
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Clinical Trials

Most Relevant Clinical Trials

  1. Safety Study of iCo-007 Intravitreal Injection to Treat Diabetic Macular Edema
  2. TENS for Testicular Pain (ICO): A Randomized Controlled Trial
  3. A Randomized, Multi-center, Phase II Study of the Safety, Tolerability and Bioactivity of Repeated I…
  4. XmAb23104 (PD1 X ICOS) and XmAb22841 (CTLA-4 X LAG3) in Treating Melanoma Prior Immune Checkpoint In…
  5. The Efficacy and Safety of Y-3 Intracalvariosseous Injection Versus Intravenous Injection in the Tre…
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