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IGF- 1R
Summary
General Info
Curated Studies
Most Correlated Studies
Epidermis from IR and IGF-1R double knockout newborn mice
Ewing sarcoma TC-71 derived cell lines resistant to anti-IGF-1R drugs
EW-5 Ewing sarcoma xenografts treated with IGF-1R inhibitor mAb (MK0646) or mTOR inhibitor (MK8669)
Lung cancer NCI-H526 xenografts treated with R1507, cisplatin and ionizing radiation
Head and neck squamous cell carcinoma (SCCHN) cells before and after figitumumab
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Literature
Most Relevant Literature
Cryo-EM studies of the apo states of human IGF1R.
Insulin-Like Growth Factor-1 Receptor Targeted Fluorescent Imaging for Gallbladder Cancer in Orthoto…
Cryo-EM Structure Reveals Polymorphic Ligand-bound States of IGF1R.
Susceptibility to autophagy inhibition is enhanced by dual IGF1R and MAPK/ERK inhibition in pancreat…
Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to T…
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Clinical Trials
Most Relevant Clinical Trials
In Vivo IGF-1R Molecular Imaging Using [68Ga]- Labelling Anti-IGF-1R Affibody Molecule
Anti-insulin-like Growth Factor-1 Receptor (IGF-1R) Antibodies in Graves' Disease and Graves' Orbito…
The Role of TSH Receptor, PPAR-r, IGF-1R, IGF and Cytokines in Different Stages of Graves’Ophthalmop…
Clinical Study of Oral IGF-1R Inhibitor in Subjects With Advanced Refractory Solid Tumors
Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors…
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