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IL 2
Summary
General Info
Curated Studies
Most Correlated Studies
CD8+ T cells anti-CD3 CD28 activated then stimulated with IL-2 or IL-2 variants H9 or H9-RET
IL-2-dependent gene expression by human regulatory T cells
Cell cycle exit induced in human T lymphoblasts by IL-2 withdrawal
CD4+ T cells from IL-2 knockout Scurfy mice
Natural killer cell transcriptional responses to IL-2, IL-12, and IL-18.
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Literature
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Location, location, location! Rewiring IL-2 circuits defines context-specific outcomes.
New sights of low dose IL-2: Restoration of immune homeostasis for viral infection.
Treg-targeted IL-2/anti-IL-2 complex controls graft-versus-host disease and supports anti-tumor effe…
IL-2-driven CD8+ T cell phenotypes: implications for immunotherapy.
IL-2-mediated hepatotoxicity: knowledge gap identification based on the irAOP concept.
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Clinical Trials
Most Relevant Clinical Trials
Low-dose IL-2 in Established T1D - The "PROREG" Study
Comparison of High-dose IL-2 and High-dose IL-2 With Radiation Therapy in Patients With Metastatic M…
T1DM Immunotherapy Using Polyclonal Tregs + IL-2
HD IL-2 + Vemurafenib in Patients With BRAF Mutation Positive Metastatic Melanoma
Safety and Biological Activity of TroVax® Vaccine Given With IL-2 in Renal Cell Carcinoma
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