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IRAK 1
Summary
General Info
Curated Studies
Most Correlated Studies
Primary macrophages infected with HIV-1 or control for 2,4, or 7d
Removal of developing autoreactive B cells in humans
Macrophage gene expression profiling in response to 4hr LPS treatment
Dendritic cells stimulated with H. pylori lysate or E. coli lysate
Melanoma cells sorted CD271+/- from patient tumors
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Literature
Most Relevant Literature
IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies.
Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants.
IRAK1 inhibition blocks the HIV-1 RNA mediated pro-inflammatory cytokine response from microglia.
Pharmacological inhibition of IRAK1 and IRAK4 prevents endothelial inflammation and atherosclerosis …
Effect of sodium butyrate regulating IRAK1 (interleukin-1 receptor-associated kinase 1) on visceral …
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Clinical Trials
Most Relevant Clinical Trials
A Phase 1/2 Study of Oral IRAK-4 Inhibitor CA-4948 in Combination With Pembrolizumab Following Stere…
IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflam…
TLR Polymorphism, ASO and Beta-hemolytic Group A Streptococcus Infections in ADHD: an Observational …
Mathematical Modeling of the Acute Inflammatory Response Following Injury
The Effects of Moxibustion on Ulcerative Colitis
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