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JAK 2
Summary
General Info
Curated Studies
Most Correlated Studies
White-to-brown metabolic conversion of adipocytes by JAK inhibition
Cooperative Signaling in the STAT3 and NF-kB Pathways in Subtypes of diffuse large B cell lymphoma
IL-2-dependent gene expression by human regulatory T cells
Melanoma and hepatoma cell lines expressing SOCS1 and SOCS3 and INFA treated
CD4+ T cells activated under Th0 conditions with or without tofacitinib
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Literature
Most Relevant Literature
JAK2-mediated Intracellular Signaling.
Computational modeling and in vitro evaluation identified natural product-Z218 as a novel Janus kina…
Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux.
Janus kinase 2 (JAK2) methylation and obesity: A Mendelian randomization study.
Allelic burden of Janus kinase 2 in a 6-month course of therapy for myeloproliferative neoplasms.
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Clinical Trials
Most Relevant Clinical Trials
Polymorphism of Janus Kinase 1 and 2 (JAK 1&2) in Patients With Alopecia Areata
Phase IIA Study of the HDAC Inhibitor ITF2357 in Patients With JAK-2 V617F Positive Chronic Myelopro…
JAK 1/2 Inhibitor, Baricitinib, in the Treatment of Adult IIM
Trial of Erlotinib in Patients With JAK-2 V617F Positive Polycythemia Vera
A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or Hi…
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