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QuickView for JAK2 (gene)


Body Atlas

Most Correlated Tissues

  1. Basophil of peripheral blood
  2. Neutrophil of bone marrow
  3. Eosinophil of peripheral blood
  4. Leukocyte (polymorphonuclear) of peripheral blood
  5. Myeloid cells of peripheral blood
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Disease Atlas

Most Correlated Diseases

  1. Budd-Chiari syndrome
  2. Myelofibrosis
  3. Erythrocytosis
  4. Congenital glucose-galactose malabsorption
  5. Multiple organ failure
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Pharmaco Atlas

Most Correlated Compounds

  1. Dimethadione
  2. Trenbolone Acetate
  3. Scopoletin
  4. 4-hydroxyestradiol-17 beta
  5. Carticaine
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. Ptger4
  2. GRAMD1B
  3. VCP
  4. STMN1
  5. EXOSC4
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. JAK2-mediated Intracellular Signaling.
  2. Computational modeling and in vitro evaluation identified natural product-Z218 as a novel Janus kina…
  3. Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux.
  4. Janus kinase 2 (JAK2) methylation and obesity: A Mendelian randomization study.
  5. Allelic burden of Janus kinase 2 in a 6-month course of therapy for myeloproliferative neoplasms.
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Clinical Trials

Most Relevant Clinical Trials

  1. Anticoagulation in Gastroesophageal Varices and JAK2 Mutation
  2. JAK2 Inhibitors RUXOLITINIB in Patients With Myelofibrosis
  3. Sympathicomimetic Agonist in Patients With Myeloproliferative Neoplasms With JAK2-mutation
  4. Elotuzumab for the Treatment of JAK2-Mutated Myelofibrosis
  5. JAK2 Mutation May Predict Response and Guide First Line Treatment in Rheumatoid Arthritis
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