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Janus kinase, JAK
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Curated Studies
Most Correlated Studies
Ovarian cancer model treated with JAK inhibitor AZD1480
White-to-brown metabolic conversion of adipocytes by JAK inhibition
Skin biopsies of atopic dermatitis patients treated with oral dual JAK/SYK inhibitor ASN002
Epithelial cells from small airway treated with interferons, Baricitinib or Ruxolitinib
CD4+ T cells activated under Th0 conditions with or without tofacitinib
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Literature
Most Relevant Literature
Janus kinase inhibition as a potential strategy for the treatment of psoriasis: state of the art and…
Targeting the JAK-STAT pathway in lymphoma: a focus on pacritinib.
De-regulation of JNK and JAK/STAT signaling in ESCRT-II mutant tissues cooperatively contributes to …
Interleukin-6 signalling: more than Jaks and STATs.
IL-7 downregulates IL-7Rα expression in human CD8 T cells by two independent mechanisms.
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Clinical Trials
Most Relevant Clinical Trials
Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or Hig…
Polymorphism of Janus Kinase 1 and 2 (JAK 1&2) in Patients With Alopecia Areata
Comparative Study of Janus Kinase (JAK) Inhibitors Vs Tumor Necrosis Factor (TNF) Inhibitors in Rheu…
A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or Hi…
Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)
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