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KSR 1
Summary
General Info
Curated Studies
Most Correlated Studies
Ectodermal and mesodermal embryoid bodies differentiated from ES cells and iPS cells
SNUhES3 human embryonic stem cells and embryoid bodies differentiated from SNUhES3
Induced pluripotent stem cells and fibroblasts from dermis of Zellweger Spectrum Disorder patients
Fibroblasts and fibroblast-reprogrammed iPSCs from childhood cerebral adrenoleukodystrophy patients
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Literature
Most Relevant Literature
KSR as a therapeutic target for Ras-dependent cancers.
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1.
A CC-SAM, for coiled coil-sterile α motif, domain targets the scaffold KSR-1 to specific sites in th…
Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Mela…
Calmodulin influences MAPK signaling by binding KSR1.
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Clinical Trials
Most Relevant Clinical Trials
[KSR-001-P01]Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristic …
[KSR-001-P02] Phase 2b/3 Study, Evaluate the Efficacy and Safety of KSR-001 in Patients With Dry Eye…
Biospecimen Collection in Assessing the Effect of Trametinib With or Without Uprosertib on Biomarker…
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