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Kinesin 8
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NextBio Summary
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Body Atlas
Most Correlated Tissues
No tissues found
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Disease Atlas
Most Correlated Diseases
No diseases found
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Pharmaco Atlas
Most Correlated Compounds
Antigens, Neoplasm
Scgb3a2 protein, mouse
Ethanol
Bleomycin
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Knockdown Atlas
Most Correlated Gene Perturbations
SLC13A1
MET
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Curated Studies
Most Correlated Studies
Hepatocytes from wildtype and Met null mice treated with hepatocyte growth factor
Gene expression changes in differentiated cortical neurospheres pre-exposed to ethanol
Effects of fescue toxicosis under chronic heat conditions
Gene expression in the kidneys and testis after low-dose-rate irradiation
Cortical neurons exposed to excitotoxic NMDA and potentially neuroprotective compounds
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Literature
Most Relevant Literature
Kinesin-8 motors: regulation of microtubule dynamics and chromosome movements.
A model of processive walking and slipping of kinesin-8 molecular motors.
Bioenergetics of the Dictyostelium Kinesin-8 Motor Isoform.
Loss of kinesin-8 improves the robustness of the self-assembled spindle in Schizosaccharomyces pombe…
The Kinesin-8 Kip3 Depolymerizes Microtubules with a Collective Force-Dependent Mechanism.
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Clinical Trials
Most Relevant Clinical Trials
Open Label, Dose Escalation Trial of Oral Eg5 Kinesin-spindle Inhibitor 4SC-205 in Patients With Adv…
Filanesib (ARRY-520) in Combination With Pomalidomide and Dexamethasone for Relapsed/Refractory (R/R…
A Phase II Study of AZD4877 (a Novel Anti-mitotic Agent) in Advanced Bladder Cancer
Additional KIF6 Risk Offers Better Adherence to Statins
Alectinib in Combination With Bevacizumab in ALK Positive NSCLC
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