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QuickView for LRRK2 (gene)


Body Atlas

Most Correlated Tissues

  1. Lung
  2. Synovial membrane
  3. Kidney medulla
  4. Spleen
  5. Bone marrow
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Disease Atlas

Most Correlated Diseases

  1. Multiple-resistant Staphylococcus aureus infection
  2. Sepsis due to Streptococcus agalactiae
  3. Systemic infection
  4. Parkinson's disease
  5. Thyroid cancer
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Pharmaco Atlas

Most Correlated Compounds

  1. 8-aminohexylamino cAMP
  2. Gonadotropins, Equine
  3. naphthalan
  4. Benzodiazepines
  5. anti-IgM
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. FGFR1
  2. PBK
  3. HSP90AB1
  4. NR5A1
  5. CD22
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression.
  2. Investigation of microglial diversity in a LRRK2 G2019S mouse model of Parkinson's disease.
  3. Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Par…
  4. Leucine-Rich Repeat Kinase-2 Controls the Differentiation and Maturation of Oligodendrocytes in Mice…
  5. LRRK2 G2019S enhances immune response pathways and aggravates asthma in mouse models.
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Clinical Trials

Most Relevant Clinical Trials

  1. Fox BioNet Project: LRRK2-002
  2. LIPAD - LRRK2 International Parkinson's Disease Study
  3. Parkinson's Disease G2019S LRRK2 Genetic Testing Program
  4. LRRK2 Mutation and Parkinson's Disease
  5. Chinese PD-LRRK2 Registry
Explore Clinical Trials Results
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