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LRRK2
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Summary
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Body Atlas
Most Correlated Tissues
Lung
Synovial membrane
Kidney medulla
Spleen
Bone marrow
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Disease Atlas
Most Correlated Diseases
Multiple-resistant Staphylococcus aureus infection
Sepsis due to Streptococcus agalactiae
Systemic infection
Parkinson's disease
Disorder of basal ganglia
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Pharmaco Atlas
Most Correlated Compounds
8-aminohexylamino cAMP
Gonadotropins, Equine
naphthalan
Benzodiazepines
anti-IgM
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Knockdown Atlas
Most Correlated Gene Perturbations
FGFR1
PBK
HSP90AB1
NR5A1
ATF7
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression.
LRRK2 negatively regulates glucose tolerance via regulation of membrane translocation of GLUT4 in ad…
Mutant LRRK2 exacerbates immune response and neurodegeneration in a chronic model of experimental co…
Leucine-rich repeat kinase 2 promotes the development of experimental severe acute pancreatitis.
Formation of templated inclusions in a forebrain α-synuclein mouse model is independent of LRRK2.
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Clinical Trials
Most Relevant Clinical Trials
Fox BioNet Project: LRRK2-002
LIPAD - LRRK2 International Parkinson's Disease Study
Parkinson's Disease G2019S LRRK2 Genetic Testing Program
LRRK2 Mutation and Parkinson's Disease
Chinese PD-LRRK2 Registry
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