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QuickView for Leflunomide (compound)


Genetic Markers

Most Correlated Genes

  1. CYP1A1
  2. STAC3
  3. CYP1B1
  4. RB1
  5. FOS
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Pathway Enrichment

Most Correlated Biogroups

  1. organic cyclic compound binding
  2. heterocyclic compound binding
  3. regulation of nitrogen compound metabolic process
  4. small molecule binding
  5. anion binding
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Curated Studies

Most Correlated Studies

  1. Renal clear cell cancer Caki-2 cells after treatment with leflunomide
  2. Livers of rats exposed to 27 agents with different mechanisms of action for toxicity
  3. Embryonic gene expression in zebrafish treated with leflunomide
  4. Livers from rats exposed to chemicals with different mechanisms of action
  5. Livers from wildtype Sprague-Dawley rats exposed to 27 chemicals
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Literature

Most Relevant Literature

  1. Leflunomide: dermatologic perspective.
  2. Leflunomide: friend or foe for systemic lupus erythematosus?
  3. Leflunomide in dermatology.
  4. Leflunomide for cytomegalovirus: bench to bedside.
  5. The SMILE study -- safety of methotrexate in combination with leflunomide in rheumatoid arthritis.
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Clinical Trials

Most Relevant Clinical Trials

  1. Leflunomide in Mild COVID-19 Patients
  2. Leflunomide to Treat Uveitis
  3. Leflunomide for Maintenance of Remission in IgG4 Related Disease
  4. Treatment With Leflunomide in Patients With Polymyalgia Rheumatica
  5. Leflunomide Treatment for IgG4-RD
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