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MEKK3
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Summary
General Info
Body Atlas
Most Correlated Tissues
Myeloid cells of peripheral blood
Monocyte of peripheral blood
Macrophage of peripheral blood
Mononuclear cell of peripheral blood
Leukocyte (polymorphonuclear) of peripheral blood
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Literature
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Somatic variants of MAP3K3 are sufficient to cause cerebral and spinal cord cavernous malformations.
Endothelial hyperactivation of mutant MAP3K3 induces cerebral cavernous malformation enhanced by PIK…
MEKK3-TGFβ crosstalk regulates inward arterial remodeling.
CCM2L (Cerebral Cavernous Malformation 2 Like) Deletion Aggravates Cerebral Cavernous Malformation T…
miR-188 promotes senescence of lineage-negative bone marrow cells by targeting MAP3K3 expression.
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