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MHC II
Summary
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Curated Studies
Most Correlated Studies
Regulatory T cells (Tregs, CD4+ TCRB+ CD25+) from CD3e- MHC II- or CD3e- MHC II+ recipient mice
Dendritic cells (CD11c+ MHC II+ LY6G+) of C57BL/6 mice
T cells adoptively transferred sorted from lymph nodes after moth cytochrome c protein treatment
Peripheral blood monocytes response to soluble MHC Class II
Cardiac purkinje (CNTN2+) cells versus ventricular myocytes (a-MHC+) gene profile
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Literature
Most Relevant Literature
MHC II immunogenicity shapes the neoepitope landscape in human tumors.
MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
Small-molecule MHC-II inducers promote immune detection and anti-cancer immunity via editing cancer …
TRIM22 negatively regulates MHC-II expression.
Combining Sequence Similarity with Physicochemical Properties to Predict Binders for MHC-II Molecule…
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Clinical Trials
Most Relevant Clinical Trials
Nivolumab Plus Relatlimab or Ipilimumab in Metastatic Melanoma Stratified by MHC-II Expression
Effect of Methyldopa on MHC Class II Antigen Presentation in Type 1 Diabetes
Vorinostat, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage …
Immunotherapy of HLA-A2 Positive Stage II-IV Melanoma Patients
Imiquimod and Tumor Lysate Vaccine Immunotherapy in Adults With High Risk or Recurrent Grade II Glio…
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