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MNK 1
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Curated Studies
Most Correlated Studies
Cervical carcinoma HeLa cells treated with MNK inhibitor eFT-508 and activated with PMA
Diffuse large B-cell lymphoma HLY1 cells overexpressing elF4E1 or eIF4E3
Breast cancer MCF7 cells EIF4E silenced and tamoxifen resistant
Natural killer cells from bone marrow of mice with TCF7 knockout
Macrophages primed with IFNg and treated with Pam3CSK4 for TLR2 stimulation
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Literature
Most Relevant Literature
Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1.
Novel deuterated Mnk1/2 protein degrader VNLG-152R analogs: Synthesis, In vitro Anti-TNBC activities…
miR-370-3p Regulates Adipogenesis through Targeting Mknk1.
Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immu…
Scribble Controls Social Motivation Behavior through the Regulation of the ERK/Mnk1 Pathway.
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Clinical Trials
Most Relevant Clinical Trials
Trial to Study the Safety of Intravenous MNK-010 in Advanced Solid Tumors
Pharmacokinetics and Safety of MNK-155 in Postsurgical Adolescent Subjects With Moderate to Severe A…
A Study to Assess the Efficacy and Safety of MNK-1411 in Duchenne Muscular Dystrophy
MNK Inhibitor AUM001 in Combination With Either Pembrolizumab or Irinotecan to Treat Metastatic Colo…
Tomivosertib (eFT-508) in Combination With PD-1/PD-L1 Inhibitor Therapy
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