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MPL protein
Summary
General Info
Curated Studies
Most Correlated Studies
Hematopoietic stem/progenitor cells (HSPC) from mutant MPL expressing, aplastic bone marrows (BM)
Cord blood CD34+ progenitor gene expression induced by dimerization of intracellular Mpl
CML K-562 cells overexpressing wildtype or mutant CALR and treated with melittin
Thrombopoietin Receptor Agonist signaling in Acute Myeloid Leukemia primary cells
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Literature
Most Relevant Literature
C-Cbl regulates c-MPL receptor trafficking and its internalization.
Research Status of TPO/c-MPL Signaling Pathway in Acute Myeloid Leukemia--Review].
c-Mpl and TPO expression in the human central nervous system neurons inhibits neuronal apoptosis.
Novel thrombopoietin mimetic peptides bind c-Mpl receptor: Synthesis, biological evaluation and mole…
Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis.
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Clinical Trials
Most Relevant Clinical Trials
A Study of the Efficacy and Safety of the LEISH-F2 + MPL-SE Vaccine for Treatment of Cutaneous Leish…
LEISH-F3 + GLA-SE and the LEISH-F3 + MPL-SE Vaccine
Study to Evaluate the Leish-111F + MPL-SE Vaccine in the Treatment of Cutaneous Leishmaniasis
Open-Label Safety Study of Three-Antigen Leishmania Polyprotein With Adjuvant MPL-SE in Healthy Adul…
Study to Evaluate the Leish-111F + MPL-SE Vaccine in the Treatment of Mucosal Leishmaniasis
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