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Nav1 1
NextBio Summary
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Curated Studies
Most Correlated Studies
Zebrafish larvae with Scn1a (Nav1.1) mutation
Dorsal root ganglia from NAV1.7, NAV1.8 and NAV1.9 knockout mice
Dorsal root ganglia after diphtheria-toxin deletion of the Nav1.8-expressing cells
Dorsal root ganglia expression profiles in a neuropathic pain model - Davis-Tabor and Scott 2006
Left atrial appendages of the heart with overexpression of TBX3
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Literature
Most Relevant Literature
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain.
Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous s…
Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mou…
Mouse with Nav1.1 haploinsufficiency, a model for Dravet syndrome, exhibits lowered sociability and …
Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility.
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Clinical Trials
Most Relevant Clinical Trials
Carbamazapine for Inherited Erythromelalgia Patients With NaV1.7 Mutations
Safety and Tolerability of Lacosamide in Patients With Gain-of-function Nav1.7 Mutations Related Sma…
An Open-Label Study to Investigate the Safety of Single Ascending Doses in Children and Adolescents …
Brugada Syndrome and Artificial Intelligence Applications to Diagnosis
Probing the Role of Sodium Channels in Painful Neuropathies
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