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Nbs1
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Body Atlas
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Disease Atlas
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Pharmaco Atlas
Most Correlated Compounds
latrunculin A
Cisplatin
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GCR2
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Curated Studies
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S. cerevisiae S88C with GCN5 deletion or graded expression of an inhibitory GCN5[F221A] allele
Transcription factors Bas1, Pho2, Gcn4, and Gcr2 knockout in yeast
Expression profile in wild type, fkh2delta and fkh2-S2A mutant yeast
S.cerevisiae gene expression profiles of rpb1 CTD site-directed mutants
Transcriptional response of S. cerevisiae to change in oxygen provision
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Literature
Most Relevant Literature
NBS1 is required for macrophage homeostasis and functional activity in mice.
NBS1 binds directly to TOPBP1 via disparate interactions between the NBS1 BRCT1 domain and the TOPBP…
Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers high-grade gliomas.
Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations an…
Structure of the human ATM kinase and mechanism of Nbs1 binding.
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Clinical Trials
Most Relevant Clinical Trials
Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage S…
A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001…
AZD1775 for Advanced Solid Tumors
Testing the Addition of an Anti-cancer Drug, BAY 1895344 ATR Inhibitor, to the Chemotherapy Treatmen…
Genetic Predictive Model Based on Single Nucleotide Polymorphisms in the DNA Repair Pathway and Drug…
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