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PDE 3
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
PDE4B
PPP2CA
DDX27
ROCK2
UBR2
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Pathway Enrichment
Most Correlated Biogroups
regulation of nitrogen compound metabolic process
response to organic substance
organic cyclic compound binding
organic cyclic compound metabolic process
regulation of RNA biosynthetic process
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Curated Studies
Most Correlated Studies
Hearts of rats exposed variety of toxicants
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
Drug Matrix In Vivo Toxicogenomic Study - Rat Heart [Affymetrix]
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Literature
Most Relevant Literature
Treatment of Cardiovascular Dysfunction with PDE3-Inhibitors in Moderate and Severe Hypothermia-Effe…
PDE3-inhibitor enoximone prevented mechanical ventilation in patients with SARS-CoV-2 pneumonia.
PDE3 Inhibitors Repurposed as Treatments for Age-Related Cognitive Impairment.
K-134, a phosphodiesterase 3 inhibitor, prevents brain damage by inhibiting thrombus formation in a …
Phosphodiesterase-3 inhibitor].
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Clinical Trials
Most Relevant Clinical Trials
Evaluation of PDE MAX
Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy
Phosphodiesterase-5 (PDE-5) Inhibition in Heart Transplant Recipients
Effects of PDE-5 Inhibition on Postprandial Hyperglycemia in Type 2 Diabetes
Effect of Pharmacologic Interaction Between ERAs and PDE-5 Inhibitors on Medication Serum Levels and…
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