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QuickView for PDK1 (gene)


Body Atlas

Most Correlated Tissues

  1. Heart
  2. Stomach pyloric
  3. Tonsil
  4. Adrenal gland cortex
  5. Stomach
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Disease Atlas

Most Correlated Diseases

  1. Tularemia
  2. Meningitis
  3. Viral infections of the central nervous system
  4. Hyperoxia
  5. Toxoplasmosis
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Pharmaco Atlas

Most Correlated Compounds

  1. Pyrilamine
  2. Clenbuterol
  3. 5-((2,6-dichlorobenzyl)sulfonyl)-3-((3,5-dimethyl-4-((2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-1,3-dihydro-2H-indol-2-one
  4. Cholesterol, HDL
  5. PIK 75
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. HIF1
  2. Bcl2l1
  3. RAB5C
  4. RAB5B
  5. RAB5A
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. PDK1 Regulates the Maintenance of Cell Body and the Development of Dendrites of Purkinje Cells by pS…
  2. Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia.
  3. Production of seedable Amyloid-β peptides in model of prion diseases upon PrPSc-induced PDK1 overact…
  4. PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhib…
  5. Tissue-specific kinase expression and activity regulate flux through the pyruvate dehydrogenase comp…
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Clinical Trials

Most Relevant Clinical Trials

  1. TQB3525 for Advanced Bone Sarcomas With PI3KA Mutations or PTEN Loss
  2. Evaluation Of The Treatment Effectiveness Of Glioblastoma / Gliosarcoma Through The Suppression Of T…
  3. 17-N-Allylamino-17-Demethoxygeldanamycin With or Without Rituximab in Treating Patients With Relapse…
  4. Triciribine Phosphate, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide in Treating Patie…
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