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Curated Studies
Most Correlated Studies
Diffuse large B-cell lymphoma Karpas-422 cells treated with allosteric PRC2 inhibitor EED226
Spinal muscular atrophy fibroblasts with PRC2:SMN-AS1-targeting or SUZ12-targeting oligos
Third instar larvae and eydiscs with E(z)-RNAi or jarid2[mb] mutations
MLL-AF9 induced leukemic bone marrow with EZH2 and EED gene knockouts
Embryonic CJ7 stem cell line with JARID2, EED or EZH2 knockout
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Literature
Most Relevant Literature
Differentiation of hPSCs to Study PRC2 Role in Cell-Fate Specification and Neurodevelopment.
Polycomb repressive complex 2 accessory factors: rheostats for cell fate decision?
Alternative splicing decouples local from global PRC2 activity.
Polycomb Repressive Complex 2 in Oncology.
Detecting Cell Compartment-Specific PRC2-RNA Interactions via UV-RIP.
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Clinical Trials
Most Relevant Clinical Trials
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia
Study of ORIC-944 in Patients With Metastatic Prostate Cancer
Hippotherapy in Children With Spinal Muscular Atrophy
A Study of ASTX727 in People With Malignant Peripheral Nerve Sheath Tumors (MPNST)
X-chromosome Inactivation, Epigenetics and the Transcriptome
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