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Protriptyline
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
SLC6A4
SLC6A2
IFI6
HSPA5
FPR1
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Pathway Enrichment
Most Correlated Biogroups
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
PODAR_RESPONSE_TO_ADAPHOSTIN_UP
EGFR_UP.V1_UP
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP
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Curated Studies
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Drug target sets for approved compounds
Broad Connectivity Map (CMAP 2.0) compound database
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (1 of 4)
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Literature
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Protriptyline block of the human ether-à-go-go-related gene (HERG) K+ channel.
In vitro studies of DNA damage caused by tricyclic antidepressants: a role of peroxidase in the side…
Pharmacological approaches to the treatment of obstructive sleep apnoea.
Medical therapy for obstructive sleep apnea: a review by the Medical Therapy for Obstructive Sleep A…
A dose-response study on the efficacy of tricyclic antidepressants on reducing morphine-withdrawal s…
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Clinical Trials
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Bioequivalency Study of Protriptyline 10 mg Tablets Under Fasted Conditions
Effect of Antibiotics on Urinary Microbiome
A Study of the Effect of Epinephrine on Platelet Reactivity in Subjects Treated With Ticagrelor
Study to Examine the Effect of Gastric Bypass Surgery on Venlafaxine ER Blood Levels
Co Enzyme Q10 Improves IVF Outcome in With Advanced Reproductive Age
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