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RIPK1
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Summary
General Info
Body Atlas
Most Correlated Tissues
Dendritic (plasmacytoid) cell
Transverse colon
Leukocyte (polymorphonuclear) of peripheral blood
Ascending colon
Sigmoid colon
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Disease Atlas
Most Correlated Diseases
Disorder of lymph node
Autoimmune disease
Primary immune deficiency disorder
Multiple organ dysfunction syndrome
Ischemia
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Leptin
dorzolamide
Paromomycin
triflusal
AEOL 10150
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Most Correlated Gene Perturbations
KLF1
SP3
RNR1
ASL
PTP4A3
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Most Correlated Studies
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Literature
Most Relevant Literature
The role and mechanism of RIPK1 in vascular endothelial dysfunction in chronic kidney disease.
Endothelial RIPK1 protects artery bypass graft against arteriosclerosis by regulating SMC growth.
The structure of mouse RIPK1 RHIM-containing domain as a homo-amyloid and in RIPK1/RIPK3 complex.
Inhibition of RIPK1 kinase does not affect diabetes development: β-Cells survive RIPK1 activation.
RIPK1 activation in Mecp2-deficient microglia promotes inflammation and glutamate release in RTT.
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Clinical Trials
Most Relevant Clinical Trials
Single Ascending Dose Study of SAR443820 in Healthy Adult Chinese and Japanese Female and Male Parti…
First-time-in-human (FTIH) Study of GSK3145095 Alone and in Combination With Other Anticancer Agents…
A Study of GFH312 in Healthy Subjects
Dose-finding Study of SAR443122 in Adult Participants With Ulcerative Colitis
Testing the Addition of an Investigational Anti-Cancer Drug, ASTX660 (Tolinapant), to a Usual Chemot…
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