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RNF168
(gene)
Summary
General Info
Body Atlas
Most Correlated Tissues
Skeletal muscle
Colon mucosa
Synovial membrane
Skin
Penis
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Disease Atlas
Most Correlated Diseases
Multiple-resistant Staphylococcus aureus infection
Placental insufficiency
Pyloric ulcer
Liver transplant disorder
Fetal growth restriction
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Most Correlated Compounds
Ethylene Glycol
Neomycin
Bithionol
prochloraz
Nisoldipine
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Knockdown Atlas
Most Correlated Gene Perturbations
MIR15A
LINC00626
HR
DDX25
FBP1
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.
BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168.
RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation.
RNF168 forms a functional complex with RAD6 during the DNA damage response.
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Clinical Trials
Most Relevant Clinical Trials
A First in Human Study of BAY2701439 to Look at Safety, How the Body Absorbs, Distributes and Excret…
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