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Rag2
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Summary
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Body Atlas
Most Correlated Tissues
Thymus gland
Hematopoietic stem cell of bone marrow
Microglial cell
Myeloid cells of peripheral blood
Macrophage of peripheral blood
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Disease Atlas
Most Correlated Diseases
Severe combined immunodeficiency disease
Pyloric ulcer
Viremia
Primary immune deficiency disorder
Thyroid cancer
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Pharmaco Atlas
Most Correlated Compounds
Anthracyclines
fragment C, human serum albumin
Thrombopoietin
flt3 ligand protein
FBLN5 protein, human
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Knockdown Atlas
Most Correlated Gene Perturbations
Ikzf1
STK38
FOXA2
CEBPA
HOXB4
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
Cutting Edge: TCR-β Selection Is Required at the CD4+CD8+ Stage of Human T Cell Development.
RAG2 involves the Igκ locus demethylation during B cell development.
Immature Lymphocytes Inhibit Rag1 and Rag2 Transcription and V(D)J Recombination in Response to DNA …
Disruption of the RAG2 zinc finger motif impairs protein stability and causes immunodeficiency.
An interdomain boundary in RAG1 facilitates cooperative binding to RAG2 in formation of the V(D)J re…
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Clinical Trials
Most Relevant Clinical Trials
Conditioning SCID Infants Diagnosed Early
Phase I/II Clinical Trial Stem Cell Gene Therapy in RAG1-Deficient SCID
Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infus…
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