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SHP 1
Summary
General Info
Curated Studies
Most Correlated Studies
GSK cancer cell line transcript profiling
Regulatory T cell expression profiling of shp-1 heterozygous and homozygous knockout BALBc mice.
Small cell lung cancer cell lines treated with LSD1 inhibitor GSK2879552
Livers from 2mo old SHP knockouts
Liver gene expression in SHP knockout, OB and SHP knockout, OB knockout and wild type mice
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Literature
Most Relevant Literature
Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity.
Multiple phosphorylation of the Cdc48/p97 cofactor protein Shp1/p47 occurs upon cell stress in buddi…
Regulation of autoimmune arthritis by the SHP-1 tyrosine phosphatase.
Cdc48/Shp1 participates in dissociation of protein complexes to regulate their activity.
SHP-1 ameliorates nonalcoholic steatohepatitis by inhibiting proinflammatory cytokine production.
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Clinical Trials
Most Relevant Clinical Trials
Improving Wellbeing of SHP Personnel at UAB
Intensive Pharmacovigilance Program for Elaprase (SHP ELA-701)
RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line…
Pembrolizumab + Platinum Doublets Without Radiation for Programmed Death-ligand 1 (PD-L1) ≥50% Local…
Topical Ruxolitinib Evaluation in Atopic Dermatitis Study 1 (TRuE AD1) - An Efficacy and Safety Stud…
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