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(e.g. Cisplatin, rs2230926, BRCA1, nitric oxide metabolic process, Lung cancer, Pancreas)
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QuickView for SHP2 (gene)


Body Atlas

Most Correlated Tissues

  1. Corpus callosum
  2. Substantia nigra reticulata
  3. Globus pallidum external
  4. Putamen
  5. Medulla
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Disease Atlas

Most Correlated Diseases

  1. Lentigo
  2. Noonan's syndrome
  3. Turner syndrome
  4. Hyperpigmentation of skin
  5. Anomaly of chromosome X
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Pharmaco Atlas

Most Correlated Compounds

  1. carbinoxamine
  2. DEFB4A protein, human
  3. tropine
  4. Nefopam
  5. Immunoglobulins
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. MIR489
  2. MIR200B
  3. SFTPC
  4. PLIN1
  5. BRDT
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. A pan-cancer analysis confirms PTPN11's potential as a prognostic and immunological biomarker.
  2. The Dengue Virus Nonstructural Protein 1 (NS1) Interacts with the Putative Epigenetic Regulator DIDO…
  3. Deficiency of the Src homology phosphatase 2 in podocytes is associated with renoprotective effects …
  4. Non-structural protein 1 (NS1) of dengue virus detection correlates with severity in primary but not…
  5. α-Actinin-4 recruits Shp2 into focal adhesions to potentiate ROCK2 activation in podocytes.
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Clinical Trials

Most Relevant Clinical Trials

  1. First-in-Human Study of the SHP2 Inhibitor BBP-398 in Patients With Advanced Solid Tumors
  2. A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutat…
  3. SHP2 Inhibitor ET0038 Monotherapy in Patients With Advanced Solid Tumors
  4. SHP2 Inhibitor ET0038 Monotherapy in Patients With Advanced Solid Tumors
  5. SHP2 Inhibitor BBP-398 in Combination With Nivolumab in Patients With Advanced Non-Small Cell Lung C…
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