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QuickView for SMN complex (compound)


Genetic Markers

Most Correlated Genes

  1. No genes found
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Pathway Enrichment

Most Correlated Biogroups

  1. No biogroups found
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Curated Studies

Most Correlated Studies

  1. Spinal muscular atrophy fibroblasts with PRC2:SMN-AS1-targeting or SUZ12-targeting oligos
  2. Motor neuron-like NSC-34 cell RNA immunoprecipitated in associated with SMN1 protein
  3. Spinal motor neurons derived from iPSCs of spinal muscular atrophy patients and healthy controls
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Literature

Most Relevant Literature

  1. Identification and structural analysis of the Schizosaccharomyces pombe SMN complex.
  2. Sumoylation regulates the assembly and activity of the SMN complex.
  3. TOR signaling regulates liquid phase separation of the SMN complex governing snRNP biogenesis.
  4. Interaction of 7SK with the Smn complex modulates snRNP production.
  5. Structural basis for Gemin5 decamer-mediated mRNA binding.
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Clinical Trials

Most Relevant Clinical Trials

  1. Mechanisms of Cell Death in Spinal Muscular Atrophy
  2. Neural Indications of Stress-Induced Mental Overload
  3. Hippotherapy in Children With Spinal Muscular Atrophy
  4. A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia
  5. Investigation of Brain Nitrogen in Partial Ornithine Transcarbamylase Deficiency (OTCD) Using 1 H MR…
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