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STK11
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Summary
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Body Atlas
Most Correlated Tissues
Granulocyte-macrophage progenitor cell of bone marrow
Macrophage of peripheral blood
Ascending colon
Bone marrow
Testis seminiferous tubule
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Disease Atlas
Most Correlated Diseases
Neurocutaneous syndrome
Polyp of intestine
Placental insufficiency
Infection due to Corynebacterium
Testicular cancer
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Tetracaine
carcinine
Riluzole
Lidoflazine
diethyl phthalate
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Most Correlated Gene Perturbations
Mcs5
Gjd2
LOC284241
STK11
SNHG15
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
LKB1 delays atherosclerosis by inhibiting phenotypic transformation of vascular smooth muscle cells.
Tumor loss-of-function mutations in STK11/LKB1 induce cachexia.
LKB1 Positively Regulates Dendritic Cell-induced T Cell Immunity and Suppresses Tumor Development.
Sex-specific role of sensory neuron LKB1 on metabolic stress-induced mechanical hypersensitivity and…
Liver kinase B1 (LKB1) in murine erythroid progenitors modulates erythropoietin setpoint in associat…
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Clinical Trials
Most Relevant Clinical Trials
Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors
Daratumumab in STK11 Mutated NSCLC
Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locall…
A Study of JAB-21822 in Advanced or Metastatic NSCLC With KRAS p.G12C and STK11 Co-mutation and Wild…
Combination Treatment (Talazoparib Plus Avelumab) for Stage IV or Recurrent Non-Squamous Non-Small C…
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