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Sertraline
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
SLC6A4
UGT2B4
HLA-DQB1
UPB1
CYP2B7P
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Pathway Enrichment
Most Correlated Biogroups
response to organic substance
response to stress
anion binding
small molecule binding
response to organic cyclic compound
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Curated Studies
Most Correlated Studies
Cerebrocortical cells treated with blood-brain barrier penetrant clinic-tested drugs
Danio rerio larvae exposed to SSRIs Fluoxetine and Sertraline
Drug Matrix In Vitro Toxicogenomic Study - Rat Hepatocytes [Affymetrix]
Drug Matrix In Vitro Toxicogenomic Study - Rat Hepatocytes [Codelink]
Drug Matrix In Vivo Toxicogenomic Study - Rat Heart [Codelink]
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Literature
Most Relevant Literature
The relation between dosage, serum concentrations, and clinical outcome in children and adolescents …
Analysis of sertraline in postmortem fluids and tissues in 11 aviation accident victims.
Sensitive determination of sertraline by capillary electrophoresis with dispersive liquid-liquid mic…
Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo.
Diffuse alveolar damage and recurrent respiratory failure secondary to sertraline.
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Clinical Trials
Most Relevant Clinical Trials
Vortioxetine vs Sertraline in Mexicans
Flushes and Sertraline Trial
A Pharmacokinetic Study of the Coadministration of LY2216684 With Sertraline
Personalized Sertraline Dosing in Patients With Depression
Special Investigation Of Long Term Use Of Sertraline.
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