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Correlation Engine 2.0
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Clear Search sequence regions
(e.g. Lung cancer, Adipose tissue, Laser capture microdissection, Trichostatin A, MDM2)
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QuickView for Smo (gene)


Body Atlas

Most Correlated Tissues

  1. Atrioventricular node
  2. Ciliary ganglion
  3. Appendix
  4. Tongue
  5. Superior cervical ganglion
Explore Body Atlas Results

Disease Atlas

Most Correlated Diseases

  1. Injury of eye region
  2. Gastroesophageal reflux disease
  3. Other leukemia
  4. Disease due to Orthopoxvirus
  5. Stachybotryotoxicosis
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Pharmaco Atlas

Most Correlated Compounds

  1. Carbimazole
  2. Buthionine Sulfoximine
  3. Staurosporine
  4. manganese chloride
  5. ipriflavone
Explore Pharmaco Atlas Results

Knockdown Atlas

Most Correlated Gene Perturbations

  1. Kmt2a
  2. Mllt3
  3. USP51
  4. BAZ1B
  5. COX1
Explore Knockdown Atlas Results

Curated Studies

Most Correlated Studies

  1. Cancer Gene Census - mutations in cancer genes
  2. OMIM - Curry-Jones syndrome
  3. Induced pluripotent stem cells and embryonic fibroblasts isolated by RNA FACS for endogenous Sox2
  4. Myeloid progenitors with Zfx conditional deletion and Myc overexpression
  5. Somatic mutations in patients with pancreatic cysts
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Literature

Most Relevant Literature

  1. Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing li…
  2. Characterization of the sorbitol dehydrogenase SmoS from Sinorhizobium meliloti 1021.
  3. Coupling of Smoothened to inhibitory G proteins reduces voltage-gated K+ currents in cardiomyocytes …
  4. Expression of an Extracellular Protein (SMU.63) Is Regulated by SprV in Streptococcus mutans.
  5. Whole Exome Sequencing of SMO, BRAF, PTCH1 and GNAS in Odontogenic Diseases.
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Clinical Trials

Most Relevant Clinical Trials

  1. LDE225 for Patients With PTCH1 or SMO Mutated Tumors
  2. Study of Vismodegib in Advanced Gastric Adenocarcinoma Patients With SMO Overexpression
  3. Phase 2 Dasatinib Combo With Smoothened (SMO) Antagonist (BMS-833923)
  4. Dasatinib Combination Therapy With the Smoothened (SMO) Inhibitor BMS-833923 in Chronic Myeloid Leuk…
  5. Comparative Study of Gamma-hydroxy Butyrate Versus Oxazepam in the Treatment of Alcohol Withdrawal S…
Explore Clinical Trials Results
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