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TMEM106B
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Summary
General Info
Body Atlas
Most Correlated Tissues
Medulla oblongata
Medulla
Globus pallidus
Corpus callosum
Cervix
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Disease Atlas
Most Correlated Diseases
Vasculitis
Thyroid eye disease
Disorder of eye
Kidney transplant failure and rejection
Huntington's disease
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Pharmaco Atlas
Most Correlated Compounds
2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine
allyl alcohol
isonicotinamide
Amikacin
10058-F4 compound
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Knockdown Atlas
Most Correlated Gene Perturbations
Htt
CLDN18
PDE1C
MECOM
MIR376A1
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Literature
Most Relevant Literature
TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss.
A role of the frontotemporal lobar degeneration risk factor TMEM106B in myelination.
Aged Tmem106b knockout mice display gait deficits in coincidence with Purkinje cell loss and only li…
Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment s…
Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice.
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