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Tie2
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NextBio Summary
General Info
Body Atlas
Most Correlated Tissues
Superior cervical ganglion
Atrioventricular node
Ciliary ganglion
Appendix
Skeletal muscle psoas
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Disease Atlas
Most Correlated Diseases
Venous malformation
Neurocutaneous syndrome
Vascular disorder
Lung cancer
11p partial monosomy syndrome
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Pharmaco Atlas
Most Correlated Compounds
Todralazine
graveoline
GW8510
Carticaine
Trypsin
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Knockdown Atlas
Most Correlated Gene Perturbations
KDM7A
INTS8
BCAR1
BAG3
CABIN1
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Curated Studies
Most Correlated Studies
Prostate cancers derived by conditional (PB-Cre) manipulation of PTEN, TP53, MYC or ERG genes
Single retinal Muller glial cells from rd1 & rhodopsin knockout mouse models of retinitis pigmentosa
Common myeloid progenitors with high or low levels of reactive oxygen species
Embryonic fibroblast time course of Oct4, Sox2, Klf4, and Myc overexpression
Embryonic stem H9 and CT2 cells depleted of JMJD1C
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Literature
Most Relevant Literature
Gene control of tyrosine kinase TIE2 and vascular manifestations of infections.
Activated protein C binds directly to Tie2: possible beneficial effects on endothelial barrier funct…
Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TF…
Normalization of Tumor Vessels by Tie2 Activation and Ang2 Inhibition Enhances Drug Delivery and Pro…
Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearanc…
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Clinical Trials
Most Relevant Clinical Trials
Validation of Tie2 as the First Tumour Vascular Response Biomarker for VEGF Inhibitors: VALTIVE1
A Study of ARRY-614 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome
A Study of ARRY-614 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes
ESK981 in Treating Patients With Metastatic Castrate-Resistant Prostate Cancer
Trebananib With or Without Low-Dose Cytarabine in Treating Patients With Acute Myeloid Leukemia
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