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Toca-1
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Summary
General Info
Body Atlas
Most Correlated Tissues
No tissues found
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Disease Atlas
Most Correlated Diseases
No diseases found
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Pharmaco Atlas
Most Correlated Compounds
Saline Solution, Hypertonic
Sodium Chloride
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Knockdown Atlas
Most Correlated Gene Perturbations
let-60
F59G1.6
osm-7
pie-1
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Curated Studies
Most Correlated Studies
O-GlcNAcylation ChIP analysis in O-GlcNAc cycling enzymes mutants in C. elegans
DPY-27 binding in embryos and fed L1 larvae
MES-4 binding in mes-4 RNAi C. elegans early embryos by ChIP-chip
Worm embryo genome occupancy by dosage compensation complex proteins with smo-1 knockdown
C. elegans gene expression after entrainment to 12hr light-dark and warm-cold cycles
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Literature
Most Relevant Literature
Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis.
A complex of ZO-1 and the BAR-domain protein TOCA-1 regulates actin assembly at the tight junction.
Myogenesis defect due to Toca-1 knockdown can be suppressed by expression of N-WASP.
toca-1 is in a novel pathway that functions in parallel with a SUN-KASH nuclear envelope bridge to m…
Phosphoinositides and membrane curvature switch the mode of actin polymerization via selective recru…
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Clinical Trials
Most Relevant Clinical Trials
The Toca 5 Trial: Toca 511 & Toca FC Versus Standard of Care in Patients With Recurrent High Grade G…
A Study of Toca 511 & Toca FC in Patients With Recurrent High Grade Non-Muscle Invasive Bladder Canc…
A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid T…
A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511
A Study of the Safety of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Subject…
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