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Tpl-2
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NextBio Summary
General Info
Body Atlas
Most Correlated Tissues
Leukocyte (polymorphonuclear) of peripheral blood
Basophil of peripheral blood
Joint synovium
Nipple cross-section
Eosinophil of peripheral blood
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Disease Atlas
Most Correlated Diseases
Toxoplasmosis
Anomaly of chromosome pair 12
Rift valley fever
Infection due to Enterobacteriaceae
Bacterial infection due to Bacillus
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Pharmaco Atlas
Most Correlated Compounds
CP 690,550
HAMLET complex, human
STI571
MRK 003
Interleukin-12
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Knockdown Atlas
Most Correlated Gene Perturbations
PALB2
ANKRD2
PEBP1
ITK
TMEM173
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus.
Tpl2 promotes neutrophil trafficking, oxidative burst, and bacterial killing.
Tpl2 Promotes Innate Cell Recruitment and Effector T Cell Differentiation To Limit Citrobacter roden…
The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation.
Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
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Clinical Trials
Most Relevant Clinical Trials
Clinical Trial for Non-responders Who Previously Participated in Eltrombopag Studies TPL 103922 or T…
KLâ‚„Surfactant Treatment in Patients With ARDS
Evaluation of a New Predictive Test of Preterm Birth in Case of Threatened Preterm Labor
Trial to Assess the Safety and Tolerability of Lucinactant for Inhalation in Premature Neonates
Effect of Probiotics on the Preterm Delivery Rate in Pregnant Women at High Risk for Preterm Birth
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