QuickView for ZNF420 (gene)

1. H3K9me3 facilitates hypoxia-induced p53-dependent apoptosis through repression of APAK.
2. ARF-mediated SUMOylation of Apak antagonizes ubiquitylation and promotes its nucleolar accumulation …
3. Apak competes with p53 for direct binding to intron 1 of p53AIP1 to regulate apoptosis.
4. ARF-dependent regulation of ATM and p53 associated KZNF (Apak) protein activity in response to oncog…
5. KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis.

There were no clinical trials for ZNF420