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adenosine receptor antagonists
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
PDK4
PDE4B
FABP4
IGFBP1
PCK1
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Pathway Enrichment
Most Correlated Biogroups
DODD_NASOPHARYNGEAL_CARCINOMA_DN
heterocyclic compound binding
organic cyclic compound binding
PILON_KLF1_TARGETS_DN
cytosol
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Curated Studies
Most Correlated Studies
Butyrate mediated prevention of colorectal cancer in a mouse model
Nonsense-mediated mRNA decay-inhibited LCLs from families predisposed to breast cancer
Granulocytes treated with caffeine to inhibit nonsense-mediated decay
Preadipocytes from 3T3-L1 fibroblasts induced with adipogenic drugs for 4hr to become adipocytes
Bone marrow-derived mesenchymal stromal cell line IMSC3 upon adipocyte differentiation
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Literature
Most Relevant Literature
Quantitative structure-activity relationship study on affinity profile of a series of 1,8-naphthyrid…
Pharmacophore mapping and in silico screening to identify new potent leads for A(2A) adenosine recep…
Lesion of the caudal ventrolateral medulla prevents the induction of hypertension by adenosine recep…
Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine rece…
Adenosine receptor subtype-selective antagonists in inflammation and hyperalgesia.
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Clinical Trials
Most Relevant Clinical Trials
PROTECT-1: A Study of the Selective A1 Adenosine Receptor Antagonist KW-3902 for Patients Hospitaliz…
PROTECT-2: A Study of the Selective A1 Adenosine Receptor Antagonist KW-3902 for Patients Hospitaliz…
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer
Combining Low Oxygen Therapy and an Adenosine A2a Receptor Antagonist to Improve Functional Mobility…
A Phase II Study to Test the Efficacy of AB928 (Dual Adenosine Receptor Antagonist) and AB122 (a PD1…
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