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aldosterone antagonists
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CYP3A4
HLA-DQB1
NR3C2
EDNRA
DLX5
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Pathway Enrichment
Most Correlated Biogroups
response to organic substance
organic cyclic compound binding
heterocyclic compound binding
regulation of nitrogen compound metabolic process
cytosol
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Curated Studies
Most Correlated Studies
Colorectal cancer and squamous cell carcinoma cell lines treated with spironolactone
Quadriceps of dystrophic mice treated with a combination of spironolactone and lisinopril
Prostate cancer LAPC-4 cells treated with 28 different androgen-modulators
Hearts of rats exposed variety of toxicants
Livers of rat exposed to variety of hepatotoxic compounds
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Literature
Most Relevant Literature
Antiarrhythmic potential of aldosterone antagonists in atrial fibrillation.
Cost-effectiveness of aldosterone antagonists for the treatment of post-myocardial infarction heart …
Design and rationale of a retrospective clinical effectiveness study of aldosterone antagonist thera…
Update on aldosterone antagonists use in heart failure with reduced left ventricular ejection fracti…
Aldosterone antagonists and chronic aortic regurgitation: promising but not quite ready for prime ti…
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Clinical Trials
Most Relevant Clinical Trials
Effect of Betablocker or Aldosterone Antagonist Therapy on Patients With Liver Cirrhosis
Efficacy of Aldosterone Antagonist Therapy for Prevention of New Atrial Fibrillation
Aldosterone Antagonist Therapy for Adults With Heart Failure and Preserved Systolic Function
Unilateral Primary Aldosteronism, Mineralocorticoid Antagonists Versus Surgical Treatment
High-dose Aldosterone Antagonist for Acute Decompensated Heart Failure
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