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allosteric in inhibitors
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Curated Studies
Most Correlated Studies
Glioblastoma stem-like cells treated with MALT1 allosteric inhibitor mepazine
Diffuse large B-cell lymphoma Karpas-422 cells treated with allosteric PRC2 inhibitor EED226
Hepatocellular carcinomas treated with PI3K/mTOR inhibitors
Breast cancer cell lines and xenografts treated with PI3KA or AKT inhibitors
Breast cancer MDA-MB-231 cells treated with RHO GTPase inhibitor DC-RC-063
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Literature
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Optimizing the Multimerization Properties of Quinoline-Based Allosteric HIV-1 Integrase Inhibitors.
Discovery of arylsulfonamides as a novel class of allosteric integrase inhibitors with antiviral act…
Covalent Allosteric Inhibitors of Akt Generated Using a Click Fragment Approach.
Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 Å resolution: Routes to inhibitor optim…
New Promise and Opportunities for Allosteric Kinase Inhibitors.
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Clinical Trials
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A Study of BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid …
Phase I Dose Escalation Study With an Allosteric AKT 1/2 Inhibitor in Patients
PIPA: Combination of PI3 Kinase Inhibitors and PAlbociclib
ABL001 for the Treatment of Chronic Myeloid Leukemia in Patients Who Are on Therapy With Tyrosine Ki…
Identifying Mechanisms of Resistance to mTOR Inhibitors in Cancer
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