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alpha hydroxytamoxifen
Summary
General Info
Curated Studies
Most Correlated Studies
Breast adenocarcinoma MCF7 cells treated with various environmental chemicals
Neural 3D tissue constructs from H1 ESC-derived precursor cells treated with neurotoxic chemicals
MCF 7 breast cancer cells treated with 4-hydroxytamoxifen and siRNA against ESR1 or RAR-alpha
MCF7 breast cancer cells treated with tamoxifen metabolites in the presence or absence of estrogen.
SKBR3 cells effects with hydroxytamoxifen and/or anti-GPR30 RNAi
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Literature
Most Relevant Literature
Assessment of the impact of CYP3A polymorphisms on the formation of α-hydroxytamoxifen and N-desmeth…
Effect of N,N-didesmethyltamoxifen upon DNA adduct formation by tamoxifen and alpha-hydroxytamoxifen…
Interactions of the stereoisomers of alpha-hydroxytamoxifen with human hydroxysteroid sulfotransfera…
Formation of tamoxifen-DNA adducts in human endometrial explants exposed to alpha-hydroxytamoxifen.
Formation of tamoxifen-DNA adducts via O-sulfonation, not O-acetylation, of alpha-hydroxytamoxifen i…
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Clinical Trials
Most Relevant Clinical Trials
Afimoxifene in Reducing the Risk of Breast Cancer in Women With Mammographically Dense Breast
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