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QuickView for aminoimidazole carboxamide ribonucleotide (compound)


Genetic Markers

Most Correlated Genes

  1. DDIT3
  2. PPP1R10
  3. ATP2B1-AS1
  4. NABP1
  5. TMEM189-UBE2V1
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Pathway Enrichment

Most Correlated Biogroups

  1. FISCHER_DREAM_TARGETS
  2. regulation of nucleic acid-templated transcription
  3. regulation of RNA biosynthetic process
  4. MARSON_BOUND_BY_E2F4_UNSTIMULATED
  5. heterocyclic compound binding
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Curated Studies

Most Correlated Studies

  1. Combinatorial targeting of glycolysis and oxidative phosphorylation suppresses tumor growth
  2. Neural progenitor cells (NPCs) derived from iPSCs of pontocerebellar hypoplasia (PCH) patients
  3. Leydig cells (MA-10) treated with 10uM forskolin only or in combination with 1mM AICAR
  4. Breast cancer BT474 cells treated with AICAR
  5. AICAR monophosphate and AICAr riboside accumulation affects on transcription in yeast
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Literature

Most Relevant Literature

  1. Prior Treatment with AICAR Causes the Selective Phosphorylation of mTOR Substrates in C2C12 Cells.
  2. Independent and combined effects of calorie restriction and AICAR on glucose uptake and insulin sign…
  3. AICAR attenuates postoperative abdominal adhesion formation by inhibiting oxidative stress and promo…
  4. Aminoimidazole carboxamide ribonucleotide (AICAR) inhibits the growth of retinoblastoma in vivo by d…
  5. Analysis of microRNA expression profile induced by AICAR in mouse hepatocytes.
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Clinical Trials

Most Relevant Clinical Trials

  1. Pemetrexed in Advanced Non-small Cell Lung Cancer
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