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amyloidogenic proteins
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CD69
CLEC4E
CCL5
CXCL13
IL1B
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Pathway Enrichment
Most Correlated Biogroups
CHEN_METABOLIC_SYNDROM_NETWORK
HALLMARK_INTERFERON_GAMMA_RESPONSE
response to other organism
MARKEY_RB1_ACUTE_LOF_DN
GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP
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Curated Studies
Most Correlated Studies
Adult and neonatal astrocytes exposed to beta amyloid ex vivo
P7 microglia treated with Aß42 peptides and prostaglandin E receptor 4 (EP4) agonist ONO-AE1-329
Microglial cells from EP2 knockout mice injected with fibrillary amyloid beta peptide (Aβ42)
Monocyte-derived macrophage response to wildtype or Gly72Asp variant SAA1 protein treatment
Effect of hIAPP aggregation on gene expression by mouse bone marrow-derived macrophages after 1
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Literature
Most Relevant Literature
Verteporfin is a substrate-selective γ-secretase inhibitor that binds the amyloid precursor protein …
The orphan drug dichloroacetate reduces amyloid beta-peptide production whilst promoting non-amyloid…
Acute inhibition of AMPA receptors by perampanel reduces amyloid β-protein levels by suppressing β-c…
MiR-340 Reduces the Accumulation of Amyloid-β Through Targeting BACE1 (β-site Amyloid Precursor Prot…
Members of the vertebrate contactin and amyloid precursor protein families interact through a conser…
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Clinical Trials
Most Relevant Clinical Trials
AMDX-2011P Retinal Tracer in Subjects With Neurodegenerative Diseases Associated With Amyloidogenic …
PET Imaging of the Translocator Proteine Ligands (TSPO) With [18 F] DPA-714 Biomarker of NeuroInflam…
Mitochondrial Function in Transthyretin Amyloidosis
Cardiac Contractility Modulation Therapy in Amyloid Cardiomyopathy Patients With Heart Failure
Institutional Registry of Amyloidosis
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