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QuickView for antidepressive agents (compound)


Genetic Markers

Most Correlated Genes

  1. FOS
  2. ATF3
  3. HMGCS1
  4. CA3
  5. CYP51A1
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. response to organic substance
  3. organic cyclic compound binding
  4. heterocyclic compound binding
  5. PILON_KLF1_TARGETS_DN
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Curated Studies

Most Correlated Studies

  1. Genomics Assisted Toxicity Evaluation system study - Human Hepatocytes
  2. Amitriptyline treatment of aged 3xTg Alzheimer’s disease model mice
  3. Acute myeloid leukemia cell lines treated with all-trans-retinoic acid and/or tranylcypromine
  4. Adipocytes treated with tranylcypromine or siRNA against AOF RFK or PHF21A
  5. PBMC of patients with major depression (MD) or subsyndromal symptomatic depression (SSD)
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Literature

Most Relevant Literature

  1. Exercise improves sexual function in women taking antidepressants: results from a randomized crossov…
  2. Antidepressants in adolescence.
  3. Antidepressants and depression].
  4. Synthesis of 2,4-dihydroxychalcone derivatives as potential antidepressant effect.
  5. Molecular and cellular mechanisms of antidepressant action.
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Clinical Trials

Most Relevant Clinical Trials

  1. ANGIOtensin Agents and Reduction of AntiDEPRESSANT Drugs' Prescription (The ANGIODEPRESSANTS' Study)
  2. Efficacy of Deep Anaesthesia With Isoflurane as a Fast-response Antidepressant Agent
  3. Tapering Off Antidepressants
  4. Disentangling Pharmacological and Expectation Effects in Antidepressant Discontinuation
  5. Antidepressant Incomplete Response Depression
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